B. Higgens (Warrendale, PA: Materials Research Society), 551566. A Toxiol. Oral (in diet) administration to mice and rats showed no effects or changes that could be correlated to tribomechanically micronized clinoptilolite-supplementation. Water SA 36, 437444. Studies on free radicals, antioxidants, and co-factors. doi: 10.1155/2016/7047238, Miranda-Trevino, J. C., and Coles, C. A. R, Zeolite can help reduce and chelate bioaccumulation of some heavy metals. It is important to note that M-cells apical and basolateral sides, which communicate with Peyers patches, are polarized (Society for Mucosal Immunology, 2012) and one may hypothesize that, due to this particular phenotype, M-cells retain clinoptilolite particles or silica particles released from the clinoptilolite material (tuff), which do not enter the blood system (Nizet et al., 2018) and act locally on this tissue. Best of all, theres zero risk. Due to clinoptilolites remarkable ion-exchange and adsorption properties and consequent detoxifying effects, it has proven useful in the elimination of a variety of contaminants from the body or in amelioration of the intestinal status. In Zeolite A, the Al-framework is balanced out by the maximum number of cation exchange sites; it has high cation contents and superior exchange capacities. https://www.ncbi.nlm.nih.gov/pubmed/29630078, Zeolites are very promising for improving environment protection, detoxication, human nutrition status and immunity, separation of various biomolecules and cells, construction of biosensors and detection of biomarkers of various diseases, proper drug/gene delivery, antioxidant regulation, and tissue engineering. Adsorption of water by clinoptilolite and glauconite. If the clinoptilolite-containing product dosage is lower or if it is not administered at the time of alcohol consumption, this effect may not be visible as shown by Gandy et al. The superantigens generally encompass some bacterial exotoxins and viral products with a potent non-specific immuno-stimulatory effect on large T-cells fractions. Ther. doi: 10.1053/rvsc.2001.0487, Papaioannou, D. S., Kyriakis, S. C., Papasteriadis, A., Roumbies, N., Yannakopoulos, A., and Alexopoulos, C. (2002). Comparative Study of Endocytosis between Normal Cells and Those that had Become Tumor Cells. R, Zeolite has also been reported to reduce symptoms of Gastroesophageal Refulx Disease (GERD), such as heartburn, discomfort, and pain, and may act as a replacement for some cases where Proton Pump Inhibitors (PPIs) are used. Also, clinoptilolite-containing natural tuffs come with small quantities of other trace elements, and clinoptilolite is always pre-loaded with various cations. These effects were documented in animals and humans for clinoptilolite material used as supplementation to regular diet in a powdered form. Am. Longev. Furthermore, the authors show that the re-adsorption of Pb particles that leach from the solid material may occur as well; for lead this process occurred at pH 1.5 and 2. Classical acute, subacute, and chronic tests on rats and mice were performed as well. In a study performed by Ivkovic et al. Superoxide ion: generation and chemical Implications. Reach a Customer Happiness agent They are HAPPY to help. RRR, QuikClot brand hemostatic agent, which is used to stop severe bleeding,contains a calcium-loaded form of zeolite found in kaolin clay. However, concerns have been raised in the public about the safety of clinoptilolite materials for in vivo applications. doi: 10.2741/1918, Katsoulos, P. D., Karatzia, M. A., Boscos, C., Wolf, P., and Karatzias, H. (2016). 70, 346352. 43, 181196. doi: 10.1089/acm.2016.0414, Davenward, S., Bentham, P., Wright, J., Crome, P., Job, D., Polwart, A., et al. 33, 423430. RR R R, Zeolite may release aluminum in the body. Zeolites are microscopic, porous minerals that cluster to form larger aggregates with small individual cavities, making them naturally occurring adsorbent substances. This is important, as hydrogen peroxide dissociates into hydrogen ion H+ and hydrogen peroxide radical (HO2), and during the acid-activation process H+ ions are brought to the negatively-charged species on the material surface. London: Academic press, 744749. R, Zeolite may help with nutrient absorption. RR, Zeolites are microporous materials (natural and synthetic) that are used for a variety of applications:catalysts and as molecular sieves, for separating and sorting various molecules, for water and air purification, including removal of radioactive contaminants, for harvesting waste heat and solar heat energy, for adsorption refrigeration, as detergents,technology in space ships and computer chips, etc. (2004). FIGURE 1. (2012). Technol. Amazon.com: Suspended Solutions - Zeolite Clinoptilolite - 90 Capsules - Responsibly Mined - All Natural Mineral Detox Removes Chemicals Safely and Effectively - Restores Gut Health and Boosts Immunity : Health & Household Health & Household Diet & Sports Nutrition Weight Loss Supplements Detox & Cleanse It is important to note that the supplementation with clinoptilolite in dairy cows may have additional benefits, such as the reduction of parturient paresis. doi: 10.1016/S0144-2449(97)00087-0, Round, J. L., and Mazmanian, S. K. (2009). Clay Sci. Have you heard about the benefits of Zeolite Clinoptilolite? 5, 4758. Rep. 11, 99104. (2016). After doing extensive research, we discovered Pure Body Extra Strength by a company called Touchstone Essentials. Timisoara: Lucrri tiinifice medicin veterinar, 610612. R, For example, in Mexican smokers, zeolite was able to counteract oxidative stress as effectively as Vitamin E. R, In clinically healthy men (both non-smokers and smokers), zeolite has shown to increase the blood levels of antioxidant enzymes (increased GSH-Px, SOD and GSH-R, and reduced the lipid peroxidation). Similarly, in the study by Fokas et al. The benefits of this approach with respect to conventional direct synthesis route from chemicals via amorphous precursors are reduced . The authors show changes on the clinoptilolite surface upon activation that resulted in an improved Ni-ions absorption. (2015). Feed Sci. What if you could be free of debilitating fatigue, keep your heart in great shape, conquer chronic disease naturally, and clear away brain fog to experience renewed clarity and focus? Effects of prolonged consumption of water with elevated nitrate levels on certain metabolic parameters of dairy cattle and use of clinoptilolite for their amelioration. doi: 10.1053/rvsc.2001.0524, Patel, M. (2016). Affinity toward aflatoxins, zearalenone, ochratoxin, and the T2 toxin was proven in vitro in the presence of aminoacids and vitamins, where the latter were not absorbed by the clinoptilolite material (Tomasevic-Canovic et al., 1996). Data has been provided on the ability of silicon-rich mineral water or silicic acid to remove Al from the human organism (Buffoli et al., 2013; Davenward et al., 2013), and this Si and Al relation has been recognized as the main evolutionary mechanism for fighting ecotoxicity of aluminum in living organisms. This is important because the gut is where many toxins and impurities are absorbed into the body. (2016). The single layer of the intestinal epithelium is protected by mucus containing mucin glycoproteins where immunoglobulin A (IgA) and antimicrobial peptides prevent interaction of microbiota with the cell surface. These toxins build up in our bodies affecting our sleep, memory, concentration, weight, and even inflammation (1, 2, 3, 4). 116, 30293085. The generally accepted and studied clinoptilolite effects on the human body in vivo. doi: 10.1186/1477-3163-5-1. Similar results were, however, observed in animals supplemented with vitamins E and C as well (Madhusudhan et al., 2009). Atlas of Zeolite Framework Types, 6th Edn. R, In the liver liver, zeolite can prevent further damage the of liver after hepatectomy by reducing oxidative stress. (2001b). In conclusion, clinoptilolite materials tested in the scientific literature proved to be generally safe for in vivo applications even though each material seems to retain its own physical-chemical characteristics and exerts specific biological effects that cannot be readily transferable to other materials. Mesopor. Med. R, Increases IL-10 (but reduces inflammatory response in LPS challenge) R R, Increases Lipid-Bound Sialic Acid (LSA) R, IL-8 was released without a clear pattern by any treatment, but its production was considerably higher in MMDM treated with sepiolite NC or talc, compared with clinoptilolite NC. Clinoptilolites positive immunomodulatory effects in similar conditions may be due to the interactions of clinoptilolite particles in the intestine with microfold cells (M-cells) (Figure 3). Role of oxygen radicals in DNA damage and cancer incidence. Reproduction and progeny growth in rats fed clinoptilolite in the presence or absence of dietary cadmium. 34, 589593. Doctoral Thesis, University of Sydney, Campertown. We were so impressed that we reached out to the company about making this zeolite available to our readers. 21, 135147. Pure Body Extra Strength will give you a way to free yourself of toxins, alkalize the body, strengthen your immunity and much more. J. Carcinog. Zeolites possess unique and outstanding physical and chemical properties. doi: 10.1016/j.chom.2007.09.013. Here you can find the strongest tactics science has to offer in overcoming and improving chronic disease. doi: 10.18054/pb.v119i3.5434, Wang, L. C. (2012). Pingitore, A., Lima, G. P., Mastorci, F., Quinones, A., Iervasi, G., and Vassalle, C. (2015). Indeed, different studies have shown that clinoptilolite materials provide direct detoxifying performance in vivo. Food Chem Toxicol. Nutr. Pharmacol. doi: 10.1080/19443994.2015.1011707, anli, M., and Abali, Y. 91, 18381845. By aiding in the removal of toxins, zeolite lightens this load, indirectly supporting immune function. Nano- and microsized zeolites as a perspective material for potentiometric biosensors creation. doi: 10.1007/s12011-013-9777-6, Yang, M., and Brackenbury, W. J. Gaikwad, R. W., and Warade, A. R. (2014). 2). Reactive oxygen species: role in the development of cancer and various chronic conditions. Environ. 23, 738744. Zeolite is a collective name for minerals and chemical compounds within the group of silicates, with some prominent ones:Clinoptilolite (aluminum),Sepiolite (magnesium) Analcime, Chabazite,Heulandite, Natrolite, Phillipsite, and Stilbite. Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability. Front. Recently, the application of a specific natural zeolite material, clinoptilolite, has been documented in veterinary and human medicine. A pilot study on the ability of clinoptilolite to absorb ethanol in vivo in healthy drinkers: effect of gender. As a result, it is been used in many industrial applications ranging from environmental remediation to oral. However, conclusive statements on the exact applications and benefits of clinoptilolite-based materials in humans should be carefully investigated and analyzed for each specific clinoptilolite material as the mechanisms of action may have correlations with the specific materials physical and chemical properties. Curr. It commonly occurs as a devitrification product of volcanic . And its backed up by the gold standard in instrumentation Malvern particle size testing. FIGURE 2. For example, a proper mining process with adequate cleaning, sieving, de-hydrating, and pre-milling processes, along with elemental and microbiological examination of the clinoptilolite materials, might be considered among essential requirements for ensuring purity and quality (in relation to the high clinoptilolite content in the tuff) of the final materials for in vivo consumption. Laurino, C., and Palmieri, B. Lett. R, Lead-induced Attention Deficit Hyperactivity Disorder (ADHD)may be able to be counteracted by zeolite. Were on a mission to touch one million families with goodness. Aminov, R. I., and Mackie, R. I. It turns out, Touchstone is as passionate about prevention and natural treatments as we are, so they agreed to reserve 500 bottles of Pure Body Extra Strength at an incredibly low price, exclusively for our readers. J. Evidence was provided on the role of cross-talking between the adaptive immune system and gut microbiota by selective generation of immune responses to bacteria that consequently stimulate the innate system and production of IgA. Furthermore, a high capacity of zeolite lead adsorption occurs in the pH range 311 (Payne and Abdel-Fattah, 2004) and the leaching of lead from lead-preloaded clinoptilolite occurs mainly in pH under 1, which is not relevant to conditions in the human body, as shown by Petrakakis et al. (2013). doi: 10.1007/s11356-013-1748-0. Interestingly, in the pH 3 and higher Pb, the leakage was less than 1%, while at pH 1 the leakage was observed up to 20% of the initial lead content. 18, 15011507. Res. These characteristics make them very useful in a variety of applications including agronomy, ecology, certain manufacturing, industrial processes, medicine, and cosmetics. Vet. 7:1491. doi: 10.3389/fmicb.2016.01491, Saribeyoglu, K. (2011). J. Gen. Virol. Ueki, A., Yamaguchi, M., Ueki, H., Watanabe, Y., Ohsawa, G., Kinugawa, K., et al. Commun. Maisanaba, S., Pichardo, S., Puerto, M., Gutirrez-Praena, D., Camen, A. M., and Jos, A. Life Sci. Interdiscip. Although clinoptilolite's chemical formula varies with composition, a typical representation is . 73, 20592069. Orbital Chromatogr. While evaluating possible clinoptilolite immunomodulatory effects in the intestine, it should be emphasized that M-cells can uptake nano- and submicro-particles, which can probably induce changes in the redox homeostasis in a cell (Igarashi, 2015). Protective effects of zinc-bearing clinoptilolite on broilers challenged with Salmonella pullorum. Chem. Lymphocytes stimulation by silicates, which also act as superantigens, was already shown for different silicate materials in in vitro conditions and this mechanism may underlie immunomodulation activity of clinoptilolite in the intestine as well (Ueki et al., 1994; Aikoh et al., 1998). Adsorption of divalent lead Ions by zeolites and activated carbon: effects of pH, temperature, and ionic strength. doi: 10.2174/0929867033456477, Ivkovic, S., Deutsch, U., Silberbach, A., Walraph, E., and Mannel, M. (2004). doi: 10.1186/1475-2891-7-29, Buffoli, B., Foglio, E., Borsani, E., Exley, C., Rezzani, R., and Rodella, L. F. (2013). 1. The cause of these outcomes could be attributed to the fact that plants growing in soil that has zeolite added develop a robust root system deep in the soil, increasing the efficiency of. May 26, 2023 by Alex Chivers The Benefits of Zeolite Clinoptilolite for Health and Wellness have gained an increasing amount of attention in recent years. 20, 201207. All these documented effects are due to the clinoptilolite capacity to adsorb harmful substances in the gastrointestinal tract that are not confined only to micotoxins and ammonia but include heavy metals and organic compounds as well. Zeolite is a mineral that is anti-inflammatory, an antioxidant, and helpful for clearing pores 1. Mercury, arsenic, lead, cadmium, pesticides, and volatile organic compounds just scratch the surface of what our bodies have to fight against daily. 79, 165169. The retrovirus/superantigen hypothesis of multiple sclerosis. doi: 10.1155/2016/2428153, Sabbioni, A., Ferrario, C., Milani, C., Mancabelli, L., Riccardi, E., Di Ianni, F., et al. SKP generated the main idea and wrote the manuscript, generated and shaped presented hypotheses, performed literature search and analysis, prepared the figures and tables, discussed and systematized all literature data. (2015). And because these zeolite particles are encapsulated within water molecule clusters, it is delivered in a liquid spray that is easy to use (just a few sprays, morning, noon, and night) with no odor, no taste, and no hassle. doi: 10.1023/B:MCBI.0000049134.69131.89, Valpoti, H., Graer, D., Turk, R., urii, D., Vince, S., Folnoi, I., et al. Other routes and factors may induce ROS in the organism as well, such as ROS produced through the activity of xanthine oxidase, in reactions of hypoxanthine to xanthine and xanthine to uric acid conversions, where molecular oxygen is reduced to superoxide anion, followed by a generation of hydrogen peroxide (Valko et al., 2004). The effect of conditioning with NaCl, KCl and HCl on the performance of natural clinoptilolites removal efficiency of Cu2+ and Co2+ from Co/Cu synthetic solutions. A controlled production of ROS is indeed essential to the bodys homeostasis (Covarrubias, 2008), while an excessive production of ROS is known to cause damage to the DNA, proteins, and lipids (Gulam and Ahsan, 2006). R 25, 15551569. R, For example, zeolite nanoparticles can also deliver DOPA (precursor to Dopamine)into the central nervous system. Lactic acid bacteria improves Peyers patch cell-mediated Immunoglobulin A and tight-junction expression in a destructed gut microbial environment. Clin. R, Also in the liver, zeolites have a protective effect on hepatocytes during anticancer therapy using Adriamycin (doxorubicin). doi: 10.1016/j.jhazmat.2010.05.067, Hayakawa, K., Mouri, Y., Maeda, T., Satake, I., and Sato, M. (2000). Even though the efficacy and potential of clinoptilolite materials in medicine seems high, questions have been raised on to possible clinoptilolite effects on physiologically relevant elements, i.e., micronutrients and trace elements, or effects on important processes in the organism. The Benefits of Zeolite Clinoptilolite. Poult. Finally, clinoptilolites antioxidant effects and restoration of antioxidant defense mechanisms may also be linked to the positive general systemic impact. AF performed literature search on physical-chemical properties of clinoptilolite and wrote parts of the manuscript related to clinoptilolite chemistry. Clin. doi: 10.1016/j.ydbio.2008.04.041, Cutovic, M., Lazovic, M., Vukovic-Dejanovic, V., Nikolic, D., Petronic-Markovic, I., and Cirovic, D. (2017). In vivo, the acid concentrations of the intestine are substantially lower than those used in industrial activation process. Because there is one natural mineral that can clear out the toxic garbage thats been holding you back, so you can feel better than you have in years. This structural stability is an essential element for in vivo applications. For example, zeolite can enhance the delivery of Fluorouracil in colorectal cancer models. Sci. Indeed, ROS induces cell and tissue damage when the inflammation is initiated as a mechanism for restoration of the bodys homeostasis. Kotova, D. L., Artamonova, M. N., Krysanova, T. A., Novikova, L. A., and Belchinskaya, L. I. Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: new perspectives for therapy. R, When combined with Black Seed (Nigella Sativa), zeolite may have beneficial effects on weight gain and antioxidant levels in those with Type 2 Diabetes. However, other types of zeolites (e.g., phillipsite, chabazite) and clay minerals may dominate the mineral tuff assemblage, and properties of such materials may vary in the widest sense with respect to the final mineral content (Cejka, 2005). doi: 10.1007/s00405-016-4058-6, Ryoo, I. G., Lee, S. H., and Kwak, M. K. (2016). (2013b). Health. And, yes, its safe for kids. Different physical-chemical properties between clinoptilolite and clays, e.g., kaolinite were documented accordingly in the literature (Ghiara et al., 1999; Miranda-Trevino and Coles, 2003; Payra and Dutta, 2003; Hecht, 2005; Svoboda and ulcov, 2008; Bibi, 2012; Dimowa et al., 2013; Jurki et al., 2013). Health B Crit. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Technol. (2012). Immunol. Biochar, bentonite and zeolite supplemented feeding of layer chickens alters intestinal microbiota and reduces campylobacter load. Therefore, we propose that this clinoptilolite-induced M-cells communication with Peyers patches, as similarly shown by Pavelic et al. 38, 18931899. R R, NO released from Co-ion exchanged zeolite-A can also inhibit platelet aggregation and adhesion of human platelets. No effects of clinoptilolite on physiological mineral levels have been observed in cows (Katsoulos et al., 2005a; Valpoti et al., 2017). 7, 215220. Zeolites and Ordered Mesoporous Materials: Progress and Prospects: The 1st FEZA School on Zeolites, Prague, Czech Republic. RRR, When combined with Butyrate, zeolite is able to improve pancreatic digestive enzymes, improve the villi in the intestines, and also increase antioxidant levels inside the gut. Proposed model of clinoptilolite positive immunomodulatory effect in the intestinal epithelium (denoted with red arrows) through interaction of clinoptilolite tuff particles with microfold cells (M-cells). 71, 5966. The observed local immunomodulatory effects of clinoptilolite involve the induction of immune responses through Peyers patches and/or possible positive effects on microbial intestinal populations through still unknown mechanisms. 4, 255259. Clin. Hazard. Chem. R R R, Finely-ground clinoptilolite inhibited protein kinase B (c-Akt), induced the expression of p21WAF1/CIP1 and p27KIP1 tumor suppressor proteins, and blocked the growth in several cancer cell lines. A reduced binding of 3[H]8-hydroxy-2-(di-n-propylamino)tetralin (3H-8-OH-DPAT) to 5-HT(1A) receptors in mammary carcinoma-bearing mice was normalized in animals supplemented by tribomechanically-micronized clinoptilolite. 11, 114. 34, 10871096. Sci. Joughehdoust, S., and Manafi, S. (2008). Ultrafine <20 m (TBA ground) Activated - high efficiency. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. An indirect systemic detoxification effect attributed to clinoptilolite-based material supplementation in the diet of both animals and humans was documented in other organs as well, e.g., liver. Clinoptilolite is a naturally occurring zeolite used in the nuclear industry as an effective barrier to prevent problematic radionuclide movement (Spence and Shi, 2004 ). Polym. Theyll even refund your money if youre not happy with the product, less return shipping of course. J Cancer Res. (2015). Toxicity of lead: a review with recent updates. EFSA evaluated and proved the zeolite-clinoptilolite non-toxicity for animal feed at doses of 10000 mg/kg. Ding, C., Fan, X., and Wu, G. (2017). 115, 418424. Bingham S., colonic protein metabolism and colorectal cancer. Zeolite Detox: Benefits of a Clinoptilolite Heavy Metal Cleanse 36, 95102. Evolution and ecology of antibiotic resistance genes. 320, 111. J. doi: 10.1093/ibd/izx042, Oliveira, E. P., Burini, R. C., and Jeukendrup, A. Enterex: anti-diarrheic drug based on purified natural clinoptilolite. When you use zeolite clinoptilolite, you can reap the following benefits: Boosts Your Immune System R, For example, zeolite 4A inhibited melanin synthesis induced by alpha-melanocyte-stimulating hormone (alpha-MSH) in melanoma cells. Effects of long-term feeding dairy cows on a diet supplemented with clinoptilolite on certain serum trace elements. For example, detrimental roles of the end-products of protein fermentation, such as ammonia, have been recognized on the colonic microbiota and epithelial health, in particular on the colonocytes life span and function (Hughes and Magee, 2000; Yao et al., 2016; Hamid Said, 2018). In a recent article, Turkish clinoptilolite was activated with hydrogen peroxide, which acts as a weak acid, to improve Ni2+ ions removal from aqueous solutions (anli and Abali, 2016). They are interconnected with ROS and activity of Nrf2 (Paveli et al., 2001b; Katic et al., 2006). Mesop. Biosci. R R, When combined with Palygorskite(attapulgite), zeolite can help increase body weight gain, feed intake, nutrient digestibility, as well as increase Secretory IgA (SIGA)levels. Hosp. Mitochondrial Generation of reactive oxygen species and its role in aerobic life. Clin. Importantly, no effects on the protein retention values were observed and the protein deposition was not altered (Poulsen and Oksbjerg, 1995; Laurino and Palmieri, 2015). Rahman, K. (2007). Acad. Anticancer Res. (2007). Still, presented studies provide intriguing data on positive medical effects for this type of materials, especially effects on the immune system and detoxification, all substantiated by so far presented safe profile. Their molecular structure is a dense network of AlO4 and SiO4 that generates cavities where water and other polar molecules or ions are inserted/exchanged. These gastrointestinal cells are known to initiate mucosal immunity responses on the apical membrane of the M-cells and to allow the transport of microbes and particles across the epithelial cell layer from the gut lumen to the lamina propria where interactions with immune cells occur (Mabbott et al., 2013). Activation-induced cell death in human peripheral blood lymphocytes after stimulation with silicate in vitro. (2009). doi: 10.1021/acs.chemrev.5b00407. 53, 297303. Signal. The mineral assemblies of the most common zeolite occurrences in nature are clinoptilolite- and mordenite-containing tuffs, in which the zeolite clinoptilolite and mordenite content is high (80% and over). 2016:1580967. doi: 10.1155/2016/1580967, Colella, C. (2011). J. Toxicol. Probl. Miner. In this study, endurance-trained subjects were recruited and supplemented with a clinoptilolite/dolomite/maca-based product (Panaceo Sport). M-cells are found in the GALT of Peyers patches, a rich lymphoid tissue that communicates with intestinal epithelial cells and the microbiome of the intestine by diverse immunomodulation processes as well as in the MALT of other parts of the gastrointestinal tract. (2000). Clay Miner. This immunostimulation occurs upon simultaneous interaction of the superantigen with MHC class II molecules and T-cell receptors. The first comprehensive acute, subchronic, and chronic toxicology evaluation of a clinoptilolite material in vivo was performed by Paveli et al. Indeed, the microbiota-clinoptilolite interaction may also underlie the observed immunomodulatory mechanism as well. Zeolites also appear to help with digestion and, most importantly, they may also help remove toxic metals from the body. (2001). 770827, the Serbian Ministry of Education and Science Project III44006, the Slovenian Research Agency (ARRS) Project Grant No. Removal of heavy metal and other cations from wastewater using zeolites, Sep. Sci. I have listed out 12 benefits of a zeolite detox from removing heavy metals to easing hangovers! doi: 10.3892/ijo.12.6.1355, PubMed Abstract | CrossRef Full Text | Google Scholar. R, For example in humans, zeolite can improve tight junction function and normalize Zonulin (ZO-1) and Interleukin 10 (IL-10) levels. 117, 121129. School of Medicine, Virginia Commonwealth University, United States, Aristotle University of Thessaloniki, Greece. Appl. For example, in the study of Lamprecht et al. R, For example, when combined with chitosan and hyaluronic acid, zeolite may be a useful antimicrobial in vascular grafts. Assessment of Pb retention coefficient and nutrient utilization in growing pigs fed diets with added clinoptilolite. Hughes, R., and Magee, E. A. Morillas-Ruiz, J. M., and Hernndez-Snchez, P. (2015). In addition, EDTA and clinoptilolite supplementation exerted a protective effect on the brain tissue of mice intoxicated with lead by inducing antioxidant mechanisms and greater activity levels of catalase, SOD, glutathione peroxidase, and glutathione (Basha et al., 2013). Hecht, K. The variety of zeolites application is indeed a consequence of their porous structure: pores form negatively charged channels and cavities, which are occupied with positively charged alkali, and alkali earth monovalent (i.e., Na+, K+), and divalent (i.e., Ca2+) ions, OH-groups or H2O molecules, which can be easily exchanged by other molecules and cations from the surroundings (Figure 2). Their cleansing process and nanosizing technology is hands-down the most advanced weve seen, yielding the only zeolite on the market that can effectively detoxify the entire body on a cellular level. To our knowledge, no negative effects on immune cells or tissue were documented in the scientific literature so far. Microbiol. (2008). In these cows, dietary administration of clinoptilolite alleviated the nitrate burden to the body and reduced the negative systemic effects of nitrates (Katsoulos et al., 2015). In-field evaluation of clinoptilolite feeding efficacy on the reduction of milk aflatoxin M1 concentration in dairy cattle. Sports Med.
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